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DPBQ
CAS No. 7029-89-2
DPBQ( 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione | ZINC1620467 )
Catalog No. M26174 CAS No. 7029-89-2
DPBQ is a factor that activates p53.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 153 | In Stock |
|
| 5MG | 259 | In Stock |
|
| 10MG | 374 | In Stock |
|
| 25MG | 562 | In Stock |
|
| 50MG | 759 | In Stock |
|
| 100MG | 1014 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDPBQ
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NoteResearch use only, not for human use.
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Brief DescriptionDPBQ is a factor that activates p53.
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DescriptionDPBQ is a factor that activates p53.(In Vitro):DPBQ induces apoptosis and death and selectively affects 4N cells.DPBQ can specifically induce the expression and phosphorylation of p53.Deletion of TP53 can restore the proliferation of tetraploid cells in the presence of DPBQ.
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In VitroDPBQ elicits apoptosis and cell death and is selective for effects in 4N cells. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells. Knockdown of TP53 restores proliferation of tetraploid cells in the presence of DPBQ.
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In Vivo——
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Synonyms2,3-Diphenylbenzo[g]quinoxaline-5,10-dione | ZINC1620467
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PathwayApoptosis
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Targetp53
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Recptor5-HT1| Dopamine Receptor| GABA
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Research Area——
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Indication——
Chemical Information
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CAS Number7029-89-2
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Formula Weight362.38
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Molecular FormulaC24H14N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 2.94 mg/mL (8.11 mM)
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SMILESO=C1c2ccccc2C(=O)c2nc(-c3ccccc3)c(nc12)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.David B. Fick, et al. Tetrahydroindolone and purine derivatives linked to arylpiperazines. US 6770638 B2
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