B220
CAS No. 112228-65-6
B220( —— )
Catalog No. M26068 CAS No. 112228-65-6
B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 420 | In Stock |
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| 5MG | 425 | In Stock |
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| 10MG | 562 | In Stock |
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| 25MG | 849 | In Stock |
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| 50MG | 1097 | In Stock |
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| 100MG | 1535 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameB220
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NoteResearch use only, not for human use.
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Brief DescriptionB220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).
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DescriptionB220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).(In Vitro):B220 inhibits the neutrophil release of reactive oxygen species, as well as the intracellular generation of reactive oxygen species. The inhibition is not achieved through direct oxygen radical scavenger activity of B220, and B220 has no immediate effects on the activity of the assembled oxidase. The neutrophil capability to phagocytose fluorescein-labeled opsonized yeast cells is reduced by B220. Cells preincubated with B220 (10 μg/mL) and then stimulated with the formylated peptide fMLP mobilize fewer C3 receptors on their surface than the control cells .
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In VitroB220 is an antiviral agent which can inhibit the growth of HSV-1, HSV-2 and human cytomegalovirus (CMV). B220 inhibits neutrophil release of reactive oxygen species, as well as intracellular generation of reactive oxygen species. The inhibition is not achieved through direct oxygen radical scavenger activity of B220, and B220 has no immediate effects on the activity of the assembled oxidase. The neutrophil capability to phagocytose fluorescein-labeled opsonized yeast cells is reduced by B220. Cells preincubated with B220 (10 μg/mL) and then stimulated with the formylated peptide fMLP mobilize fewer C3 receptors on their surface than the control cells.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHSV
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RecptorSK?channels
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Research Area——
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Indication——
Chemical Information
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CAS Number112228-65-6
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Formula Weight318.424
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Molecular FormulaC20H22N4
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Purity>98% (HPLC)
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Solubility——
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SMILESCN(C)CCn1c2ccccc2c2nc3cc(C)c(C)cc3nc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Crystalline forms of potassium channel modulators. WO2020086456A1.
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