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Fiacitabine

CAS No. 69123-90-6

Fiacitabine( NSC-382097 | FIAC )

Catalog No. M15648 CAS No. 69123-90-6

A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 218 In Stock
2MG 128 In Stock
5MG 198 In Stock
10MG 283 In Stock
25MG 454 In Stock
50MG 603 In Stock
100MG 809 In Stock
200MG 1088 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Fiacitabine
  • Note
    Research use only, not for human use.
  • Brief Description
    A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively.
  • Description
    A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively, shows minimal cytotoxicity; more potent than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine.HSV Infection Phase 2 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC-382097 | FIAC
  • Pathway
    Microbiology/Virology
  • Target
    HSV
  • Recptor
    HSV
  • Research Area
    Infection
  • Indication
    HSV Infection

Chemical Information

  • CAS Number
    69123-90-6
  • Formula Weight
    371.1042
  • Molecular Formula
    C9H11FIN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 37 mg/mL
  • SMILES
    O=C1N=C(N)C(I)=CN1[C@H]2[C@@H](F)[C@@H]([C@@H](CO)O2)O
  • Chemical Name
    2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodo-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lopez C, et al. Antimicrob Agents Chemother. 1980 May;17(5):803-6. 2. Allaudeen HS, et al. J Biol Chem. 1982 Oct 25;257(20):11879-82. 3. Schinazi RF, et al. Antimicrob Agents Chemother. 1983 Jul;24(1):95-103.
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