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Home - Products - PI3K/Akt/mTOR signaling - mTOR - Autogramin-1

Autogramin-1

CAS No. 2375541-73-2

Autogramin-1( —— )

Catalog No. M26065 CAS No. 2375541-73-2

Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Autogramin-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.
  • Description
    Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM. Autogramin-1 also inhibits Rapamycin (mTORC1)-induced autophagy with IC50 of 0.44 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    mTOR
  • Recptor
    P2X3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2375541-73-2
  • Formula Weight
    485.56
  • Molecular Formula
    C23H27N5O5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 6.94 mg/mL (14.29 mM)
  • SMILES
    CCCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)Nc1nc2CCN(Cc2s1)C(=O)OC(C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.
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