5-Iodo-indirubin-3-monoxime

CAS No. 331467-03-9

5-Iodo-indirubin-3-monoxime( —— )

Catalog No. M26036 CAS No. 331467-03-9

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 267 Get Quote
50MG 1224 Get Quote
100MG 1674 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    5-Iodo-indirubin-3-monoxime
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).
  • Description
    5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    331467-03-9
  • Formula Weight
    403.179
  • Molecular Formula
    C16H10IN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 67.5 mg/mL (167.42 mM)
  • SMILES
    O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(I)cc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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