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2,2,5,7,8-Pentamethyl-6-Chromanol
2,2,5,7,8-Pentamethyl-6-Chromanol
CAS No. 950-99-2
2,2,5,7,8-Pentamethyl-6-Chromanol( PMC )
Catalog No. M25001 CAS No. 950-99-2
2,2,5,7,8-Pentamethyl-6-Chromanol is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 49 | In Stock |
|
| 1G | 72 | In Stock |
|
Biological Information
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Product Name2,2,5,7,8-Pentamethyl-6-Chromanol
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NoteResearch use only, not for human use.
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Brief Description2,2,5,7,8-Pentamethyl-6-Chromanol is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.
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Description2,2,5,7,8-Pentamethyl-6-Chromanol is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.
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In Vitro——
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In Vivo——
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SynonymsPMC
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogen Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number950-99-2
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Formula Weight220.31
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Molecular FormulaC14H20O2
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (1134.76 mM; Need ultrasonic)
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SMILESCC(C)(CC1)Oc(c(C)c2C)c1c(C)c2O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.
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