BNC105

CAS No. 945771-74-4

BNC105( —— )

Catalog No. M24994 CAS No. 945771-74-4

BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 170 In Stock
5MG 155 In Stock
10MG 226 In Stock
25MG 371 In Stock
50MG 510 In Stock
100MG 686 In Stock
200MG 923 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BNC105
  • Note
    Research use only, not for human use.
  • Brief Description
    BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
  • Description
    BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    tubulin polymerization
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    945771-74-4
  • Formula Weight
    372.37
  • Molecular Formula
    C20H20O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25 mg/mL (67.14 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)
  • SMILES
    Cc1c(C(c(cc2OC)cc(OC)c2OC)=O)c(ccc(OC)c2O)c2o1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Flynn BL, et al. Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties. J Med Chem. 2011 Sep 8;54(17):6014-27.
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