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Crolibulin

CAS No. 1000852-17-4

Crolibulin( EPC2407 )

Catalog No. M26657 CAS No. 1000852-17-4

Crolibulin is an inhibitor of small molecule tubulin polymerization.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 121 In Stock
2MG 67 In Stock
5MG 109 In Stock
10MG 164 In Stock
25MG 297 In Stock
50MG 423 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Crolibulin
  • Note
    Research use only, not for human use.
  • Brief Description
    Crolibulin is an inhibitor of small molecule tubulin polymerization.
  • Description
    Crolibulin is an inhibitor of small molecule tubulin polymerization.(In Vitro):Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM. Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage.
  • In Vitro
    Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM.Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage.
  • In Vivo
    ——
  • Synonyms
    EPC2407
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    lysosomal cysteine protease| Proton pump
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1000852-17-4
  • Formula Weight
    417.263
  • Molecular Formula
    C18H17BrN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (299.57 mM)
  • SMILES
    COc1cc(cc(Br)c1OC)[C@H]1C(C#N)=C(N)Oc2c(N)c(N)ccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhao T, et al. Esomeprazole inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Invest New Drugs. 2021 Apr;39(2):337-347.
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