BM-PEG3( 1,11-Bis-maleimidotetraethyleneglycol )

Catalog No. M24856 CAS No. 86099-06-1

BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

BM-PEG3
Note

Research use only, not for human use.
Brief Description

BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

1,11-Bis-maleimidotetraethyleneglycol
Pathway

PROTACs
Target

PROTAC
Recptor

PEGs
Research Area

——
Indication

——

Chemical Information

CAS Number

86099-06-1
Formula Weight

352.34
Molecular Formula

C16H20N2O7
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

O=C(C=CC1=O)N1CCOCCOCCOCCN2C(C=CC2=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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