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Yakuchinone A

CAS No. 78954-23-1

Yakuchinone A( Yakuchinone-A )

Catalog No. M24785 CAS No. 78954-23-1

Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 161 In Stock
5MG 140 In Stock
10MG 235 In Stock
25MG 472 In Stock
50MG 672 In Stock
100MG 918 In Stock
200MG 1237 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Yakuchinone A
  • Note
    Research use only, not for human use.
  • Brief Description
    Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro.
  • Description
    Yakuchinone A is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro. Yakuchinone A inhibits the expression of cyclooxygenase-2 and of inducible nitric oxide synthase (iNOS).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Female C57BL/6 mice Dosage:50 mg/kg Administration:i.p., daily, 14 days Result:Showed a significant EAE score reduction from Day 9 to Day 15 after EAE onset.
  • Synonyms
    Yakuchinone-A
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    78954-23-1
  • Formula Weight
    312.41
  • Molecular Formula
    C20H24O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(CCCCC1=CC=CC=C1)CCC2=CC=C(O)C(OC)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang Q, Cui C, Chen CQ, Hu XL, Liu YH, Fan YH, Meng WH, Zhao QC. Anti-proliferative and pro-apoptotic activities of Alpinia oxyphylla on HepG2 cells through ROS-mediated signaling pathway. J Ethnopharmacol. 2015 Jul 1;169:99-108. doi: 10.1016/j.jep.2015.03.073. Epub 2015 Apr 16. PubMed PMID: 25891473.
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