Cart
sales@molnova.com
Home -
Products -
Immunology/Inflammation -
STING -
N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide
N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide
CAS No. 727699-84-5
N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide( —— )
Catalog No. M24737 CAS No. 727699-84-5
N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide was reported as a STING inhbiitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | In Stock |
|
| 10MG | 72 | In Stock |
|
| 25MG | 147 | In Stock |
|
| 50MG | 222 | In Stock |
|
| 100MG | 335 | In Stock |
|
| 200MG | 494 | In Stock |
|
| 500MG | 782 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameN-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide was reported as a STING inhbiitor.
-
DescriptionN-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease.
-
In VitroSN-001 targets the cyclic dinucleotide binding pocket of human STING.SN-001 (5-20 μM; 6 h) significantly impairs the induction of Ifnb mRNA, in a dose-dependent manner in L929 cells.SN-001 (10 μM; 3 h) inhibits cytosolic DNA-triggered STING signaling. Western Blot Analysis Cell Line:L929 cells Concentration:10 μM Incubation Time:3 h Result:Decreased cytosolic DNA-induced phosphorylation of STING, TBK1, IRF3, IκBα, and p65, as well as nuclear translocation of IRF3 and p65.
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetSTING
-
RecptorSTING
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number727699-84-5
-
Formula Weight476.52
-
Molecular FormulaC26H21FN2O4S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (524.64 mM)
-
SMILESCOc(ccc(NC(c(cc1)ccc1-c1ccccc1)=O)c1)c1NS(c(cc1)ccc1F)(=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
diABZI STING agonist...
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
-
STING agonist-30
STING agonist-30 is a potent activator of STING-dependent immune responses, demonstrating broad-spectrum antiviral effects against viruses such as HSV (Herpes Simplex Virus), rotavirus, and SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).
-
ADU-S100
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide agonist of STING, elicits potent and durable anti-tumor immunity when administered IT in pre-clinical syngeneic tumor models.
