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Home - Products - GPCR/G Protein - Calcium Channel - 2,3-Dihydroxy-4-methoxyacetophenone

2,3-Dihydroxy-4-methoxyacetophenone

CAS No. 708-53-2

2,3-Dihydroxy-4-methoxyacetophenone( —— )

Catalog No. M24722 CAS No. 708-53-2

2,3-Dihydroxy-4-methoxyacetophenone is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2,3-Dihydroxy-4-methoxyacetophenone
  • Note
    Research use only, not for human use.
  • Brief Description
    2,3-Dihydroxy-4-methoxyacetophenone is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.
  • Description
    2,3-Dihydroxy-4-methoxyacetophenone is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.
  • In Vitro
    2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity.
  • In Vivo
    2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    708-53-2
  • Formula Weight
    182.17
  • Molecular Formula
    C9H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC(C1=CC=C(OC)C(O)=C1O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.The ameliorating effects of 2,3-dihydroxy-4-methoxyacetophenone on scopolamine-induced memory impairment in mice and its neuroprotective activity. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6732-6.
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