NSC45586( —— )

Catalog No. M24634 CAS No. 6300-44-3

NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	35	In Stock
5MG	55	In Stock
10MG	82	In Stock
25MG	139	In Stock
50MG	203	In Stock
100MG	323	In Stock
200MG	454	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

NSC45586
Note

Research use only, not for human use.
Brief Description

NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
Description

NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PHLPP1|PHLPP2
Research Area

——
Indication

——

Chemical Information

CAS Number

6300-44-3
Formula Weight

413.4
Molecular Formula

C20H18N6NaO3+
Purity

>98% (HPLC)
Solubility

DMSO:82 mg/mL;Water:Insoluble;Ethanol:Insoluble
SMILES

CC1=CC(=C(C=C1N)N)N=NC2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O.[Na+]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jackson T C , Verrier J D , Drabek T , et al. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes.[J]. Journal of Pharmacology and Experimental Therapeutics, 2013, 347(2):516-528.

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