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Acetoacetic acid sodium salt

CAS No. 623-58-5

Acetoacetic acid sodium salt( —— )

Catalog No. M24625 CAS No. 623-58-5

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 92 In Stock
10MG 140 In Stock
25MG 228 In Stock
50MG 335 In Stock
100MG 498 In Stock
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Biological Information

  • Product Name
    Acetoacetic acid sodium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.
  • Description
    Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.
  • In Vitro
    Acetoacetic acid sodium induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes.Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    623-58-5
  • Formula Weight
    124.07
  • Molecular Formula
    C4H5NaO3
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (403.00 mM; Need ultrasonic)
  • SMILES
    CC(=O)CC(=O)[O-].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shi X, et al. Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. J Dairy Res. 2016 Nov;83(4):442-446.
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