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Anserine

CAS No. 584-85-0

Anserine( L-Anserine )

Catalog No. M24575 CAS No. 584-85-0

Anserine is a dipeptide containing β-alanine and histidine, which can be found in the skeletal muscle and brain of mammals and birds.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Anserine
  • Note
    Research use only, not for human use.
  • Brief Description
    Anserine is a dipeptide containing β-alanine and histidine, which can be found in the skeletal muscle and brain of mammals and birds.
  • Description
    Anserine is a dipeptide containing β-alanine and histidine, which can be found in the skeletal muscle and brain of mammals and birds. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice.
  • In Vitro
    ——
  • In Vivo
    Anserine (drinking water at a concentration of 2.0?g/L (equivalent to 10?mg/mouse); for 8 weeks) completely recoveres the memory deficits, improves pericyte coverage on endothelial cells in the brain, and diminishes chronic glial neuroinflammatory reactions in AβPPswe/PSEN1dE9 Alzheimer's disease (AD) model mice over 18-months old.
  • Synonyms
    L-Anserine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    584-85-0
  • Formula Weight
    240.26
  • Molecular Formula
    C10H16N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Insoluble;Water:10 mM
  • SMILES
    O=C(O)[C@H](CC1=CN=CN1C)NC(CCN)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kubomura, Daiki, Matahira, et al. Effect of anserine ingestion on the hyperglycemia and autonomic nerves in rats and humans.[J]. Nutritional Neuroscience, 2010.
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