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(-)-Butin

CAS No. 492-14-8

(-)-Butin( —— )

Catalog No. M24449 CAS No. 492-14-8

(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 211 In Stock
5MG 148 In Stock
10MG 202 In Stock
25MG 353 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    (-)-Butin
  • Note
    Research use only, not for human use.
  • Brief Description
    (-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction.
  • Description
    (-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SOD induction via the PI3K/Akt signaling pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    Akt|Nrf2|PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    492-14-8
  • Formula Weight
    272.25
  • Molecular Formula
    C15H12O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 190 mg/mL (697.89 mM)
  • SMILES
    O=C1C[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC=C13
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway.J Cell Biochem. 2012 Jun;113(6):1987-97.
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