(-)-Butin( —— )

Catalog No. M24449 CAS No. 492-14-8

(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	211	In Stock
5MG	148	In Stock
10MG	202	In Stock
25MG	353	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

(-)-Butin
Note

Research use only, not for human use.
Brief Description

(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction.
Description

(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SOD induction via the PI3K/Akt signaling pathway.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Akt
Recptor

Akt|Nrf2|PI3K
Research Area

——
Indication

——

Chemical Information

CAS Number

492-14-8
Formula Weight

272.25
Molecular Formula

C15H12O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 190 mg/mL (697.89 mM)
SMILES

O=C1C[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC=C13
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway.J Cell Biochem. 2012 Jun;113(6):1987-97.

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