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Demecolcine
CAS No. 477-30-5
Demecolcine( Colcemid | C-12669 | C 12669 | C12669 | Kolchicin | NSC-3096 )
Catalog No. M24425 CAS No. 477-30-5
Demecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 103 | In Stock |
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| 5MG | 93 | In Stock |
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| 10MG | 148 | In Stock |
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| 25MG | 236 | In Stock |
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| 50MG | 350 | In Stock |
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| 100MG | 519 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDemecolcine
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NoteResearch use only, not for human use.
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Brief DescriptionDemecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
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DescriptionDemecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
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In Vitro——
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In VivoAnimal Model:MiceDosage:0.3 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Elevated 7.8-8-fold of the hypoploid and hyperploid frequencies in metaphase II cells relative to controls.
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SynonymsColcemid | C-12669 | C 12669 | C12669 | Kolchicin | NSC-3096
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorMicrotubule/Tubulin
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Research Area——
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Indication——
Chemical Information
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CAS Number477-30-5
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Formula Weight371.43
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Molecular FormulaC21H25NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (67.31 mM)
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SMILESO=C1C=C2[C@@H](NC)CCC3=CC(OC)=C(OC)C(OC)=C3C2=CC=C1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gao Y, Ren J, Zhang L, Zhang Y, Wu X, Jiang H, Xu F, Yuan B, Yu X, Zhang J. The effects of demecolcine, alone or in combination with sucrose on bovine oocyte protrusion rate, MAPK1 protein level and c-mos gene expression level. Cell Physiol Biochem. 2014;34(6):1974-82. doi: 10.1159/000366393. Epub 2014 Nov 25.
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