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SW155246
CAS No. 420092-79-1
SW155246( —— )
Catalog No. M24384 CAS No. 420092-79-1
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 40 | In Stock |
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| 5MG | 41 | In Stock |
|
| 10MG | 65 | In Stock |
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| 25MG | 135 | In Stock |
|
| 50MG | 210 | In Stock |
|
| 100MG | 333 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 714 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSW155246
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NoteResearch use only, not for human use.
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Brief DescriptionSW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).
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DescriptionSW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNMT1
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Research Area——
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Indication——
Chemical Information
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CAS Number420092-79-1
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Formula Weight378.79
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Molecular FormulaC16H11ClN2O5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (660.00 mM)
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SMILESC1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Medina-Franco J , O Méndez-Lucio, Yoo J . Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking[J]. International Journal of Molecular Sciences, 2014, 15(2).
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