Cart
sales@molnova.com
SW155246
CAS No. 420092-79-1
SW155246( —— )
Catalog No. M24384 CAS No. 420092-79-1
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 40 | In Stock |
|
| 5MG | 41 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 135 | In Stock |
|
| 50MG | 210 | In Stock |
|
| 100MG | 333 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 714 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSW155246
-
NoteResearch use only, not for human use.
-
Brief DescriptionSW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).
-
DescriptionSW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNMT1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number420092-79-1
-
Formula Weight378.79
-
Molecular FormulaC16H11ClN2O5S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (660.00 mM)
-
SMILESC1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Medina-Franco J , O Méndez-Lucio, Yoo J . Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking[J]. International Journal of Molecular Sciences, 2014, 15(2).
molnova catalog
related products
-
Fludarabine Phosphat...
Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.
-
Calf thymus DNA
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, widely used in studying DNA binding anticancer agents and DNA binding agents that regulate DNA structure and function.
-
Mupirocin
Mupirocin(BRL-4910A) is an antibiotic of the monoxycarbolic acid class; effective against Gram-positive bacteria, including MRSA.
