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Maytansine
CAS No. 35846-53-8
Maytansine( NSC153858 | NSC 153858 | NSC-153858 | maytansine | Maitansine | Maitansina )
Catalog No. M24313 CAS No. 35846-53-8
Maytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 83 | In Stock |
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| 5MG | 53 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 174 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMaytansine
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NoteResearch use only, not for human use.
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Brief DescriptionMaytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
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DescriptionMaytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
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In VitroMaytansine, at 6x10-8 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin.
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In Vivo——
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SynonymsNSC153858 | NSC 153858 | NSC-153858 | maytansine | Maitansine | Maitansina
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorAntibiotic|microtubule
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Research Area——
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Indication——
Chemical Information
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CAS Number35846-53-8
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Formula Weight692.2
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Molecular FormulaC34H46ClN3O10
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble; Water:Insoluble
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SMILESCC(C(OC(CC(N(C)c1cc(CC(C)=CC=CC(C(C2)(N3)O)OC)cc(OC)c1Cl)=O)C1(C)OC1C(C)C2OC3=O)=O)N(C)C(C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kusari S, Lamsh?ft M, Kusari P, Gottfried S, Zühlke S, Louven K, Hentschel U, Kayser O, Spiteller M. Endophytes are hidden producers of maytansine in Putterlickia roots. J Nat Prod. 2014 Dec 26;77(12):2577-84.
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