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PC190723

CAS No. 951120-33-5

PC190723( —— )

Catalog No. M35536 CAS No. 951120-33-5

PC190723 is a bacterial cytosolic protein FtsZ inhibitor (IC50: 55 ng/ml) with antimicrobial activity that inhibits Staphylococcus spp.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PC190723
  • Note
    Research use only, not for human use.
  • Brief Description
    PC190723 is a bacterial cytosolic protein FtsZ inhibitor (IC50: 55 ng/ml) with antimicrobial activity that inhibits Staphylococcus spp.
  • Description
    PC190723 (Compound 2) is an inhibitor of the bacterial cell division protein FtsZ with an IC50 of 55 ng/ml. FtsZ-IN-3 exhibits anti-staphylococcal activity with MIC values of 1 μg/ml for MSSA and MRSA.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Antibiotic | Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    951120-33-5
  • Formula Weight
    355.75
  • Molecular Formula
    C14H8ClF2N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 200 mg/mL (562.19 mM; Ultrasonic )
  • SMILES
    O=C(N)C=1C(F)=CC=C(OCC2=NC=3C=C(Cl)C=NC3S2)C1F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132. ?
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