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Hypophyllanthin

CAS No. 33676-00-5

Hypophyllanthin( —— )

Catalog No. M24281 CAS No. 33676-00-5

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.

Purity : >98% (HPLC)

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HPLC

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Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	159	In Stock
5MG	132	In Stock
10MG	217	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Hypophyllanthin
Note

Research use only, not for human use.
Brief Description

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
Description

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
In Vitro

Hypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt.
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel|P-gp|Potassium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

33676-00-5
Formula Weight

430.5
Molecular Formula

C24H30O7
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (232.29 mM; Need ultrasonic)
SMILES

COC[C@H](Cc1c2)[C@H](COC)[C@@H](c(cc3)cc(OC)c3OC)c1c1OCOc1c2OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells.J Pharm Pharmacol. 2013 Feb;65(2):292-9.

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