Hypophyllanthin

CAS No. 33676-00-5

Hypophyllanthin( —— )

Catalog No. M24281 CAS No. 33676-00-5

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 159 In Stock
5MG 132 In Stock
10MG 217 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Hypophyllanthin
  • Note
    Research use only, not for human use.
  • Brief Description
    Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
  • Description
    Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
  • In Vitro
    Hypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel|P-gp|Potassium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    33676-00-5
  • Formula Weight
    430.5
  • Molecular Formula
    C24H30O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (232.29 mM; Need ultrasonic)
  • SMILES
    COC[C@H](Cc1c2)[C@H](COC)[C@@H](c(cc3)cc(OC)c3OC)c1c1OCOc1c2OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells.J Pharm Pharmacol. 2013 Feb;65(2):292-9.
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