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Autogramin-2

CAS No. 2375541-45-8

Autogramin-2( tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate )

Catalog No. M24090 CAS No. 2375541-45-8

Autogramin-2 potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	41	In Stock
5MG	36	In Stock
10MG	56	In Stock
25MG	107	In Stock
50MG	166	In Stock
100MG	259	In Stock
200MG	365	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Autogramin-2
Note

Research use only, not for human use.
Brief Description

Autogramin-2 potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
Description

Autogramin-2 potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
In Vitro

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In Vivo

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Synonyms

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Pathway

Autophagy
Target

Autophagy
Recptor

autophagy
Research Area

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Indication

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Chemical Information

CAS Number

2375541-45-8
Formula Weight

417.52
Molecular Formula

C21H27N3O4S
Purity

>98% (HPLC)
Solubility

DMSO:83.33 mg/mL?(199.58 mM;?Need ultrasonic)
SMILES

O=C(N1CCC2=C(SC(NC(C3=CC=C(OC(C)C)C=C3)=O)=N2)C1)OC(C)(C)C
Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.

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