Actein( —— )

Catalog No. M23848 CAS No. 18642-44-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Actein
Note

Research use only, not for human use.
Brief Description

Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients.
Description

Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders, it has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing calcium release and modulating the NF-kB and MEK pathways.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Akt
Recptor

Akt|Apoptosis|JNK
Research Area

——
Indication

——

CAS Number

18642-44-9
Formula Weight

676.9
Molecular Formula

C37H56O11
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (147.75 mM)
SMILES

C[C@H](C[C@]([C@@H]1O[C@@]11C)(O[C@@H]1O)O[C@H]1C2)[C@@H]1[C@@](C)([C@@H](C1)OC(C)=O)[C@]2(C)[C@H](CC2)[C@]1(C1)[C@@]1(CC1)[C@@H]2C(C)(C)[C@H]1O[C@@H]([C@@H]([C@H]1O)O)OC[C@H]1O
Chemical Name

——

1.Actein isolated from black cohosh promotes the function of osteoblastic MC3T3-E1 cells. J Med Food. 2014 Apr;17(4):414-23.

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