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Home - Products - Cell Cycle/DNA Damage - Potassium Channel - BMS-191095

BMS-191095

CAS No. 166095-21-2

BMS-191095( —— )

Catalog No. M23744 CAS No. 166095-21-2

BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 223 In Stock
5MG 202 In Stock
10MG 306 In Stock
25MG 550 In Stock
50MG 732 In Stock
100MG 986 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    BMS-191095
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
  • Description
    BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats with the induction of ischemia induced by middle cerebral artery occlusion (MCAO)Dosage:2.5 or 25 μg Administration:Intraventricular infusion; 30 min/60 min/24 hours before the induction of ischemia, once Result:Reduced total infarct volume in rats with of pretreat dose of 25 mg and 24 h before MCA. Induced a rapid mitochondrial depolarization.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Potassium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    166095-21-2
  • Formula Weight
    408.88
  • Molecular Formula
    C22H21ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:90 mg/mL (220.11 mM)
  • SMILES
    CC(C)([C@@H]([C@H]1N(Cc2ncc[nH]2)c(cc2)ccc2Cl)O)Oc(cc2)c1cc2C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Katakam PV, et al. Diversity of mitochondria-dependent dilator mechanisms in vascular smooth muscle of cerebral arteries from normal and insulin-resistant rats. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H493-503.
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