Olinciguat( IW-1701 )

Catalog No. M23726 CAS No. 1628732-62-6

Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	502	In Stock
5MG	454	In Stock
10MG	655	In Stock
25MG	1026	In Stock
50MG	1376	In Stock
100MG	1823	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Olinciguat
Note

Research use only, not for human use.
Brief Description

Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
Description

Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
In Vitro

——
In Vivo

——
Synonyms

IW-1701
Pathway

Metabolic Enzyme/Protease
Target

Guanylate Cyclase
Recptor

Guanylate Cyclase
Research Area

——
Indication

——

Chemical Information

CAS Number

1628732-62-6
Formula Weight

509.39
Molecular Formula

C21H16F5N7O3
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (245.39 mM; Need ultrasonic)
SMILES

NC([C@](CNc(nc(-c1nn(Cc(cccc2)c2F)c(-c2nocc2)c1)nc1)c1F)(C(F)(F)F)O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80.

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