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CG347B

CAS No. 1598426-03-9

CG347B( —— )

Catalog No. M23696 CAS No. 1598426-03-9

CG347B is a selective inhibitor of HDAC6.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	74	In Stock
5MG	69	In Stock
10MG	112	In Stock
25MG	201	In Stock
50MG	300	In Stock
100MG	417	In Stock
200MG	588	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

CG347B
Note

Research use only, not for human use.
Brief Description

CG347B is a selective inhibitor of HDAC6.
Description

CG347B is a selective inhibitor of HDAC6.
In Vitro

HtrA1 is identified as a Cisplatin (HY-17394, CDDP) resistance-related gene in NSCLC cells, while CG347B shows no effect on normalized mRNA expression or protein level of HtrA1 in NCI-H460 (CDDP-resistant) cells.CG347B (200 nM; 48 h) slightly rescues the Foxp3 expression inhibition induced by IL-4 (15 ng/mL), indicating a potential inhibition happens on histone deacetylation in naive CD4+ T cells from WT B6 mice cultured under Treg-polarizing conditions (for 1-3 d).
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

HDAC6
Research Area

——
Indication

——

Chemical Information

CAS Number

1598426-03-9
Formula Weight

283.33
Molecular Formula

C16H17N3O2
Purity

>98% (HPLC)
Solubility

DMSO:249 mg/mL?(878.83 mM;?Need ultrasonic)
SMILES

CCOC(c1cnc(NC2(CC2)c2ccccc2)nc1)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Christopher M. YATES. Metalloenzyme inhibitor compounds. WO2018165520A1.

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