RS 25344 hydrochloride

CAS No. 152815-28-6

RS 25344 hydrochloride( —— )

Catalog No. M23660 CAS No. 152815-28-6

RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 59 In Stock
50MG 99 In Stock
100MG 168 In Stock
200MG 251 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    RS 25344 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor.
  • Description
    RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor.
  • In Vitro
    RS-25344 hydrochloride (0-10 μM) is a potent inhibitor of sperm PDE activity, with an effective concentration of 0.3 nM and reaching maximum inhibition in the range of 100 nM.
  • In Vivo
    RS-25344 hydrochloride (5 mg/kg; i.p.; twice daily for 72 h) results in significant increases in stomach weights in wild type C57BL/6 mice. RS-25344 hydrochloride (1 mg/kg; i.p.; 30 min prior to food bolus) increases gastric retention in mice.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    phosphodiesterase (PDE) 4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    152815-28-6
  • Formula Weight
    411.8
  • Molecular Formula
    C19H14ClN5O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:80mg/ml(194.27mM; need ultrasonic)
  • SMILES
    O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • AN-2728

    A potent PDE4 inhibitor with IC50 of 0.49 uM.

  • Rolipram

    A potent, selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.

  • PF 05180999

    PF-05180999 (PF 5180999) is a potent, selective, brain-penetrating and orally bioavailable phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 1 nM.