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KAN0438757

CAS No. 1451255-59-6

KAN0438757( —— )

Catalog No. M23618 CAS No. 1451255-59-6

KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	206	In Stock
5MG	192	In Stock
10MG	307	In Stock
25MG	554	In Stock
50MG	745	In Stock
100MG	1014	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

KAN0438757
Note

Research use only, not for human use.
Brief Description

KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
Description

KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Glucokinase
Recptor

PFKFB3
Research Area

——
Indication

——

Chemical Information

CAS Number

1451255-59-6
Formula Weight

447.43
Molecular Formula

C21H18FNO7S
Purity

>98% (HPLC)
Solubility

DMSO:130 mg/mL (290.55 mM; Need ultrasonic)
SMILES

C1=CC(=CC(=C1)S(=O)(=O)NC2=CC(=C(C=C2)C(=O)OCCO)O)C3=C(C=CC(=C3)F)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872.

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