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Balovaptan
CAS No. 1228088-30-9
Balovaptan( RG7314 )
Catalog No. M23402 CAS No. 1228088-30-9
Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 54 | In Stock |
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| 10MG | 87 | In Stock |
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| 25MG | 177 | In Stock |
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| 50MG | 286 | In Stock |
|
| 100MG | 447 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBalovaptan
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NoteResearch use only, not for human use.
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Brief DescriptionBalovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist.
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DescriptionBalovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism.
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In VitroBalovaptan (RG7314) shows >30000-fold selectivity for hV1a over hV2 receptors, 9891-fold selectivity over hOTR (human oxytocin receptor).
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In Vivo——
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SynonymsRG7314
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PathwayGPCR/G Protein
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TargetVasopressin Receptor
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Recptorvasopressin receptor 1a
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Research Area——
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Indication——
Chemical Information
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CAS Number1228088-30-9
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Formula Weight409.91
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Molecular FormulaC22H24ClN5O
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL (152.47 mM; Need ultrasonic)
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SMILESCN1Cc(cc(cc2)Cl)c2-n2c(C(CC3)CCC3Oc3ncccc3)nnc2C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ratni H, et al. Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach. J Med Chem. 2015 Mar 12;58(5):2275-89.
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