Meropenem trihydrate

Research use only, not for human use.

Meropenem trihydrate with broad-spectrum antibacterial activity,is a carbapenem antibiotic.

Meropenem trihydrate with broad-spectrum antibacterial activity,is a carbapenem antibiotic.(In Vitro):Meropenem is intrinsically stable to dehydropeptidase-1 (DHP-1) degradation and Meropenem acts by inhibiting bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs). Meropenem possesses broad-spectrum in vitro activity, which includes activity against many Gram-positive, Gram-negative and anaerobic bacteria; Meropenem lacks activity against Enterococcus faecium, methicillin-resistant Staphylococcus aureus and Stenotrophomonas maltophilia.(In Vivo):Meropenem (60 mg/kg; intraperitoneal injection; once; SD rats) treatment significantly reduces the incidence of pancreatic infection.

Meropenem is intrinsically stable to dehydropeptidase-1 (DHP-1) degradation and Meropenem acts by inhibiting bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs). Meropenem possesses broad-spectrum in vitro activity, which includes activity against many Gram-positive, Gram-negative and anaerobic bacteria; Meropenem lacks activity against Enterococcus faecium, methicillin-resistant Staphylococcus aureus and Stenotrophomonas maltophilia.

Meropenem (60 mg/kg; intraperitoneal injection; once; SD rats) treatment significantly reduces the incidence of pancreatic infection. Animal Model:Male Sprague-Dawley rats (250-350 g) induced acute necrotizing pancreatitis Dosage:60 mg/kg Administration:Intraperitoneal injection; once Result:Significantly reduced the incidence of pancreatic infection.

SM 7338 trihydrate

GPCR/G Protein

Antibacterial

Bacterial

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119478-56-7

437.51

C17H31N3O8S

>98% (HPLC)

DMSO:90 mg/mL (205.71 mM; Need ultrasonic); H2O:12 mg/mL (27.43 mM; Need ultrasonic)

O=C(C(N12)=C(S[C@@H]3CN[C@H](C(N(C)C)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O.[H]O[H].[H]O[H].[H]O[H]

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(-20℃)

With Ice Pack

≥ 2 years