Garcinone D

CAS No. 107390-08-9

Garcinone D( —— )

Catalog No. M23282 CAS No. 107390-08-9

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Garcinone D
  • Note
    Research use only, not for human use.
  • Brief Description
    Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml.
  • Description
    Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    Keap1-Nrf2|Reactive Oxygen Species|STAT3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    107390-08-9
  • Formula Weight
    428.48
  • Molecular Formula
    C24H28O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (116.69 mM)
  • SMILES
    CC(C)(O)CCC1=C(OC)C(O)=CC(OC2=CC(O)=C(C/C=C(C)/C)C(O)=C23)=C1C3=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line.J Asian Nat Prod Res. 2008 May-Jun;10(5-6):475-9.
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