Cart
sales@molnova.com
AEM1
CAS No. 1030123-90-0
AEM1( —— )
Catalog No. M23234 CAS No. 1030123-90-0
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | In Stock |
|
| 10MG | 76 | In Stock |
|
| 25MG | 160 | In Stock |
|
| 50MG | 282 | In Stock |
|
| 100MG | 483 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAEM1
-
NoteResearch use only, not for human use.
-
Brief DescriptionAEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.
-
DescriptionAEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayNuclear Receptor/Transcription Factor
-
TargetKeap1-Nrf2
-
RecptorNRF2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1030123-90-0
-
Formula Weight379.4
-
Molecular FormulaC20H14FN3O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESC1OC2=C(O1)C=C(C=C2)CNC3=C4C(=CSC4=NC=N3)C5=CC=C(C=C5)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
toralactone
Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism
-
KI696
KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.
-
Sulforaphane
Sulforaphane (SFN) is an antioxidant agent that exerts protective effects against cell damage by activating Nrf2.
