AEM1

CAS No. 1030123-90-0

AEM1( —— )

Catalog No. M23234 CAS No. 1030123-90-0

AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 52 In Stock
2MG 30 In Stock
5MG 45 In Stock
10MG 80 In Stock
25MG 169 In Stock
50MG 291 In Stock
100MG 499 In Stock
200MG 721 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AEM1
  • Note
    Research use only, not for human use.
  • Brief Description
    AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.
  • Description
    AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Nuclear Receptor/Transcription Factor
  • Target
    Keap1-Nrf2
  • Recptor
    NRF2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1030123-90-0
  • Formula Weight
    379.4
  • Molecular Formula
    C20H14FN3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1OC2=C(O1)C=C(C=C2)CNC3=C4C(=CSC4=NC=N3)C5=CC=C(C=C5)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • Sulforaphane

    Sulforaphane (SFN) is an antioxidant agent that exerts protective effects against cell damage by activating Nrf2.

  • RA-839

    RA-839 is a potent small molecule Keap1 conjugate and selective Nrf2 signalling activator, as well as an inhibitor of Keap1/Nrf2 interaction with anticancer activity.

  • KI696 isomer

    KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.