Cart
sales@molnova.com
A-867744
CAS No. 1000279-69-5
A-867744( —— )
Catalog No. M23206 CAS No. 1000279-69-5
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 53 | In Stock |
|
| 5MG | 36 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 107 | In Stock |
|
| 50MG | 161 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameA-867744
-
NoteResearch use only, not for human use.
-
Brief DescriptionA-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
-
DescriptionA-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorAutophagy|α7 nAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1000279-69-5
-
Formula Weight402.89
-
Molecular FormulaC20H19ClN2O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:100 mg/mL (248.21 mM)
-
SMILESCCC(c(cc1-c(cc2)ccc2Cl)c(C)n1-c(cc1)ccc1S(N)(=O)=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Malysz J, et al. In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile. J Pharmacol Exp Ther. 2009 Jul;330(1):257-67.
molnova catalog
related products
-
Alisol A
Alisol A may be an autophagic inducer it has anti-cancer activity it presents inhibitory effects on cancer cell lines tested(HepG2 MDA-MB-231 and MCF-7 cells).
-
DC661
DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
-
SR-3677
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
