A-867744( —— )

Catalog No. M23206 CAS No. 1000279-69-5

A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	53	In Stock
5MG	36	In Stock
10MG	55	In Stock
25MG	107	In Stock
50MG	161	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

A-867744
Note

Research use only, not for human use.
Brief Description

A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
Description

A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

Autophagy
Recptor

Autophagy|α7 nAChR
Research Area

——
Indication

——

Chemical Information

CAS Number

1000279-69-5
Formula Weight

402.89
Molecular Formula

C20H19ClN2O3S
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (248.21 mM)
SMILES

CCC(c(cc1-c(cc2)ccc2Cl)c(C)n1-c(cc1)ccc1S(N)(=O)=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Malysz J, et al. In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile. J Pharmacol Exp Ther. 2009 Jul;330(1):257-67.

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