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A-867744
CAS No. 1000279-69-5
A-867744( —— )
Catalog No. M23206 CAS No. 1000279-69-5
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 53 | In Stock |
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| 5MG | 36 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 107 | In Stock |
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| 50MG | 161 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameA-867744
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NoteResearch use only, not for human use.
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Brief DescriptionA-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
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DescriptionA-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorAutophagy|α7 nAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number1000279-69-5
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Formula Weight402.89
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Molecular FormulaC20H19ClN2O3S
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (248.21 mM)
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SMILESCCC(c(cc1-c(cc2)ccc2Cl)c(C)n1-c(cc1)ccc1S(N)(=O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Malysz J, et al. In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile. J Pharmacol Exp Ther. 2009 Jul;330(1):257-67.
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