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Elamipretide 2TFA

CAS No. 1334953-96-6

Elamipretide 2TFA( SS-31,MTP-131,Bendavia )

Catalog No. M22969 CAS No. 1334953-96-6

Elamipretide is a novel mitochondrion-targeted antioxidant. Treatment with elamipretide significantly ameliorated LPS-induced learning and memory impairment during behavioral tests.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Elamipretide 2TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    Elamipretide is a novel mitochondrion-targeted antioxidant. Treatment with elamipretide significantly ameliorated LPS-induced learning and memory impairment during behavioral tests.
  • Description
    Elamipretide is a novel mitochondrion-targeted antioxidant. Treatment with elamipretide significantly ameliorated LPS-induced learning and memory impairment during behavioral tests. Notably, elamipretide not only provided protective effects against mitochondrial dysfunction and oxidative stress but also facilitated the regulation of brain-derived neurotrophic factor (BDNF) signaling, including the reversal of important synaptic-signaling proteins and increased synaptic structural complexity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SS-31,MTP-131,Bendavia
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1334953-96-6
  • Formula Weight
    867.84
  • Molecular Formula
    C36H51F6N9O9
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N)[C@H](CC1=CC=CC=C1)NC([C@@H](CCCCN)NC([C@@H](CC2=C(C)C=C(O)C=C2C)NC([C@@H](CCCNC(N)=N)N)=O)=O)=O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhao W , Xu Z , Cao J , et al. Elamipretide (SS-31) Improves Mitochondrial Dysfunction, Synaptic and Memory Impairment Induced by Lipopolysaccharide in Mice[J]. SSRN Electronic Journal, 2019.
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