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I-49 free base

CAS No. ——

I-49 free base( Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)- )

Catalog No. M22764 CAS No. ——

I-49 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

I-49 free base
Note

Research use only, not for human use.
Brief Description

I-49 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
Description

I-49 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
In Vitro

——
In Vivo

——
Synonyms

Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-
Pathway

MAPK/ERK Signaling
Target

Raf
Recptor

SOS1
Research Area

——
Indication

——

Chemical Information

CAS Number

——
Formula Weight

482.92
Molecular Formula

C23H26ClF3N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)C1CCOCC1)c1cccc(c1C)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.RAMHARTER JUERGEN,et al.Novel benzylamino substituted pyridopyrimidinone and derivative as SOS1 inhibitor.TW 201938557 A

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