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LUT014
CAS No. 2274819-46-2
LUT014( —— )
Catalog No. M24036 CAS No. 2274819-46-2
LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 96 | In Stock |
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| 5MG | 83 | In Stock |
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| 10MG | 113 | In Stock |
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| 25MG | 208 | In Stock |
|
| 50MG | 286 | In Stock |
|
| 100MG | 401 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLUT014
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NoteResearch use only, not for human use.
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Brief DescriptionLUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.
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DescriptionLUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetRaf
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RecptorB-Raf
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Research Area——
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Indication——
Chemical Information
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CAS Number2274819-46-2
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Formula Weight528.49
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Molecular FormulaC27H19F3N8O
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (94.61 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)
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SMILESCc1ccc2c(Nc3cccc(OC(F)(F)F)c3)nccc2c1Nc1ncccc1-c1ncnc2c1[nH]cn2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Noa Shelach. Novel braf inhibitors and use there of for treatment of cutaneous reactions. WO2019026065A2.
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