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Evocalcet

CAS No. 870964-67-3

Evocalcet( KHK7580 )

Catalog No. M22494 CAS No. 870964-67-3

Evocalcet has an activating effect on the calcium-sensing receptor (CaSR).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	32	In Stock
5MG	29	In Stock
10MG	46	In Stock
25MG	88	In Stock
50MG	142	In Stock
100MG	217	In Stock
200MG	315	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Evocalcet
Note

Research use only, not for human use.
Brief Description

Evocalcet has an activating effect on the calcium-sensing receptor (CaSR).
Description

Evocalcet has an activating effect on the calcium-sensing receptor (CaSR).
In Vitro

——
In Vivo

Animal Model:Male Sprague Dawley chronic kidney disease (CKD) rats with adenine induced secondary hyperparathyroidism (SHPT)Dosage:0.03 and 0.3 mg/kg Administration:Oral Administration; 0.03 and 0.3 mg/kg, once Result:Decreased the serum PTH and Ca levels at a dose of 0.3 mg/kg.
Synonyms

KHK7580
Pathway

GPCR/G Protein
Target

CaSR
Recptor

CaSR
Research Area

Cancer
Indication

Parathyroid CarcinomaPrimary Hyperparathyroidism

Chemical Information

CAS Number

870964-67-3
Formula Weight

374.48
Molecular Formula

C24H26N2O2
Purity

>98% (HPLC)
Solubility

DMSO:30 mg/mL (80.11 mM; Need ultrasonic and warming)
SMILES

C[C@@H](N[C@H]1CCN(C1)c1ccc(CC(O)=O)cc1)c1cccc2ccccc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Tanimura, Shinji, et al. Pharmaceutical composition containing aryl alkyl amine compound. WO 2017061621 A1.

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