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USL311

CAS No. 1373268-67-7

USL311( —— )

Catalog No. M22471 CAS No. 1373268-67-7

USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	85	In Stock
5MG	77	In Stock
10MG	123	In Stock
25MG	250	In Stock
50MG	384	In Stock
100MG	616	In Stock
200MG	Get Quote	In Stock
500MG	1277	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

USL311
Note

Research use only, not for human use.
Brief Description

USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
Description

USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

CXCR
Recptor

CXCR4
Research Area

Cancer
Indication

Solid Tumors (Phase 1)Relapsed/Recurrent GBM (Phase 2)

Chemical Information

CAS Number

1373268-67-7
Formula Weight

422.57
Molecular Formula

C24H34N6O
Purity

>98% (HPLC)
Solubility

DMSO:24 mg/mL (59.79 mM; Need ultrasonic)
SMILES

CC(C)N1CCC(CC1)N1CCCN(CC1)c1cccc(n1)C(=O)Nc1ccncc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1

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