CXCL-CXCR1/2-IN-1
CAS No. 2415653-55-1
CXCL-CXCR1/2-IN-1( —— )
Catalog No. M37526 CAS No. 2415653-55-1
CXCL-CXCR1/2-IN-1 is an orally active and potent inhibitor of the ELR+CXCL-CXCR1/2 pathway with anticancer and anti-angiogenic activity and can be used to study cardiovascular disease and cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | Get Quote |
|
| 10MG | 61 | Get Quote |
|
| 25MG | 119 | Get Quote |
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| 50MG | 196 | Get Quote |
|
| 100MG | 286 | Get Quote |
|
| 500MG | 683 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCXCL-CXCR1/2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCXCL-CXCR1/2-IN-1 is an orally active and potent inhibitor of the ELR+CXCL-CXCR1/2 pathway with anticancer and anti-angiogenic activity and can be used to study cardiovascular disease and cancer.
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DescriptionCXCL-CXCR1/2-IN-1 is an orally active and potent inhibitor of the ELR+CXCL-CXCR1/2 pathway with anticancer and anti-angiogenic activity and can be used to study cardiovascular disease and cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetCXCR
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RecptorCXCR
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Research Area——
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Indication——
Chemical Information
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CAS Number2415653-55-1
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Formula Weight383.21
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Molecular FormulaC14H8Cl2N4O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC(Cl)=CC(Cl)=C1)NC2=NC3=C(S2)C=C([N+]([O-])=O)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AMG 487
AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3.?In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively.
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TC14012
TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is a potent CXCR7 agonist with an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. TC14012 has anti-HIV activity and anti-cancer activity.
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CHIR98014
CHIR 98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
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