Cart
sales@molnova.com
Asatone
CAS No. 38451-63-7
Asatone( —— )
Catalog No. M22439 CAS No. 38451-63-7
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
|
| 5MG | 170 | In Stock |
|
| 10MG | 275 | In Stock |
|
| 25MG | 465 | In Stock |
|
| 50MG | 649 | In Stock |
|
| 100MG | 900 | In Stock |
|
| 200MG | 1190 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAsatone
-
NoteResearch use only, not for human use.
-
Brief DescriptionAsatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
-
DescriptionAsatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number38451-63-7
-
Formula Weight448.51
-
Molecular FormulaC24H32O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (222.96 mM)
-
SMILES[H][C@]12[C@H]3C(CC=C)=C[C@](OC)(C(=O)C3(OC)OC)[C@@]1(CC=C)C=C(OC)C(=O)C2(OC)OC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chang HY, et al. Asatone Prevents Acute Lung Injury by Reducing Expressions of NF-[Formula: see text]B, MAPK and Inflammatory Cytokines. Am J Chin Med. 2018;46(3):651-671.
molnova catalog
related products
-
BAY 11-7082
BAY 11-7082 a NF-κB inhibitor that selectively and irreversibly inhibits the TNF-α-inducible phosphorylation of IκBα (IC50=10 uM).
-
DMAPT
DMAPT is a water-soluble analogue of Parthenolide (PTL).
-
Eurycomalactone
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM).?Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα.
