Cart
sales@molnova.com
Naphthazarin
CAS No. 475-38-7
Naphthazarin( DHNQ,5,8-Dihydroxy-1,4-naphthoquinone )
Catalog No. M22399 CAS No. 475-38-7
Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 25MG | 32 | In Stock |
|
| 50MG | 42 | In Stock |
|
| 100MG | 59 | In Stock |
|
| 200MG | 84 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNaphthazarin
-
NoteResearch use only, not for human use.
-
Brief DescriptionNaphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation.
-
DescriptionNaphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. It triggers apoptosis and has anti-tumor effects.
-
In Vitro——
-
In Vivo——
-
SynonymsDHNQ,5,8-Dihydroxy-1,4-naphthoquinone
-
PathwayApoptosis
-
TargetApoptosis
-
Recptorapoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number475-38-7
-
Formula Weight190.15
-
Molecular FormulaC10H6O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOc1ccc(O)c2C(=O)C=CC(=O)c12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74.
molnova catalog
related products
-
Urolithin C
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
-
Kinetin riboside
A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines.
-
Ac-DEVD-CHO
Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM) with inhibitory effects on SLNT-induced apoptosis.
