XD14( —— )

Catalog No. M22392 CAS No. 1370888-71-3

XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	110	In Stock
5MG	93	In Stock
10MG	163	In Stock
25MG	330	In Stock
50MG	516	In Stock
100MG	728	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

XD14
Note

Research use only, not for human use.
Brief Description

XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).
Description

XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

BET bromodomain
Research Area

——
Indication

——

Chemical Information

CAS Number

1370888-71-3
Formula Weight

421.51
Molecular Formula

C20H27N3O5S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (296.55 mM)
SMILES

CCN(CC)S(=O)(=O)c1ccc(O)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2CC)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Daqiang P , Michel K , Lucas W , et al. Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7[J]. International Journal of Molecular ences, 2016, 17(10).

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