1-Naphthyl PP1

CAS No. 221243-82-9

1-Naphthyl PP1( 1-NA-PP 1 )

Catalog No. M22268 CAS No. 221243-82-9

1-Naphthyl PP1 is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 75 In Stock
2MG 33 In Stock
5MG 68 In Stock
10MG 93 In Stock
25MG 198 In Stock
50MG 314 In Stock
100MG 508 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    1-Naphthyl PP1
  • Note
    Research use only, not for human use.
  • Brief Description
    1-Naphthyl PP1 is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)
  • Description
    1-Naphthyl PP1 is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    1-NA-PP 1
  • Pathway
    Tyrosine Kinase
  • Target
    Src
  • Recptor
    Src
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    221243-82-9
  • Formula Weight
    317.39
  • Molecular Formula
    C19H19N5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:12 mg/mL (37.8 mM; Need ultrasonic)
  • SMILES
    CC(N1N=C(C2=C3C=CC=CC3=CC=C2)C4=C(N)N=CN=C41)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tandon M, et al. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells. PLoS One. 2013 Sep 23;8(9):e75601.
molnova catalog
related products
  • N-Acetyl-O-phosphono...

    Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.

  • RK-24466

    RK-24466 is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.

  • WH-4-023

    WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50 of 2 nM and 6 nM in cell-free assays, respectively.