9-FLUORENOL( —— )

Catalog No. M22199 CAS No. 1689-64-1

9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

9-FLUORENOL
Note

Research use only, not for human use.
Brief Description

9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.
Description

9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.Fluorenol(100 mg/kg) is reported to promote wakefulness in mice with 39% increased effectiveness over the structurally related compound, modafinil.
In Vitro

——
In Vivo

Pharmacokinetic parameters of 9-Fluorenol (100 mg/kg; i.p.) in rats
Synonyms

——
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

dopamine reuptake
Research Area

——
Indication

——

Chemical Information

CAS Number

1689-64-1
Formula Weight

182.22
Molecular Formula

C13H10O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (548.79 mM)
SMILES

OC2([H])c1ccccc1c3ccccc23
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dunn D , Hostetler G , Iqbal M , et al. Wake promoting agents: Search for next generation modafinil, lessons learned: Part III[J]. Bioorganic & Medicinal Chemistry Letters, 2012, 22(11):3751-3753.

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