Asimilobine

Research use only, not for human use.

Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun.

Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity.

Asimilobine (0.05-0.2 μM; for 24 h) shows a significant inhibition of intracellular dopamine levels in a concentration-dependent manner with an IC50 value of 0.13 μM. Asimilobine (0.15 μM) inhibits tyrosine hydroxylase (TH) and aromatic L-amino acid decarboxylase (AADC) activities at 24 h. Asimilobine also decreases TH mRNA levels and intracellular cyclic AMP levels.

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Others

Other Targets

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6871-21-2

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>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years