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Medicarpin

CAS No. 32383-76-9

Medicarpin( —— )

Catalog No. M21689 CAS No. 32383-76-9

Medicarpin a legume phytoalexin acts as an estrogen receptor (ER) agonist can stimulate osteoblast differentiation likely via ERα2 promote achievement of peak bone mass and is devoid of uterine estrogenicity; in addition given its excellent oral bioavailability it can be potential osteogenic agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 249 In Stock
5MG 275 In Stock
10MG 407 In Stock
25MG 663 In Stock
50MG 900 In Stock
100MG 1190 In Stock
200MG 1637 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Medicarpin
  • Note
    Research use only, not for human use.
  • Brief Description
    Medicarpin a legume phytoalexin acts as an estrogen receptor (ER) agonist can stimulate osteoblast differentiation likely via ERα2 promote achievement of peak bone mass and is devoid of uterine estrogenicity; in addition given its excellent oral bioavailability it can be potential osteogenic agent.
  • Description
    Medicarpin a legume phytoalexin acts as an estrogen receptor (ER) agonist can stimulate osteoblast differentiation likely via ERα2 promote achievement of peak bone mass and is devoid of uterine estrogenicity; in addition given its excellent oral bioavailability it can be potential osteogenic agent.
  • In Vitro
    Medicarpin (90 μM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 μM for P388 and P388/DOX cells).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    ROS|JNK|Bcl-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    32383-76-9
  • Formula Weight
    270.3
  • Molecular Formula
    C16H14O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (184.99 mM)
  • SMILES
    COc1cc(O[C@H]2c(ccc(O)c3)c3OC[C@@H]22)c2cc1
  • Chemical Name
    (6aS11aS)-9-methoxy-6a11a-dihydro-6H-benzofuro[32-c]chromen-3-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Effect of lead treatment on medicarpin accumulation and on the gene expression of key enzymes involved in medicarpin biosynthesis in Medicago sativa L.Environ Sci Pollut Res Int. 2014 Dec;21(24):14091-8.
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