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Medicarpin
CAS No. 32383-76-9
Medicarpin( —— )
Catalog No. M21689 CAS No. 32383-76-9
Medicarpin a legume phytoalexin acts as an estrogen receptor (ER) agonist can stimulate osteoblast differentiation likely via ERα2 promote achievement of peak bone mass and is devoid of uterine estrogenicity; in addition given its excellent oral bioavailability it can be potential osteogenic agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 249 | In Stock |
|
| 5MG | 275 | In Stock |
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| 10MG | 407 | In Stock |
|
| 25MG | 663 | In Stock |
|
| 50MG | 900 | In Stock |
|
| 100MG | 1190 | In Stock |
|
| 200MG | 1637 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMedicarpin
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NoteResearch use only, not for human use.
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Brief DescriptionMedicarpin a legume phytoalexin acts as an estrogen receptor (ER) agonist can stimulate osteoblast differentiation likely via ERα2 promote achievement of peak bone mass and is devoid of uterine estrogenicity; in addition given its excellent oral bioavailability it can be potential osteogenic agent.
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DescriptionMedicarpin a legume phytoalexin acts as an estrogen receptor (ER) agonist can stimulate osteoblast differentiation likely via ERα2 promote achievement of peak bone mass and is devoid of uterine estrogenicity; in addition given its excellent oral bioavailability it can be potential osteogenic agent.
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In VitroMedicarpin (90 μM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 μM for P388 and P388/DOX cells).
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetROS
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RecptorROS|JNK|Bcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number32383-76-9
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Formula Weight270.3
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Molecular FormulaC16H14O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (184.99 mM)
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SMILESCOc1cc(O[C@H]2c(ccc(O)c3)c3OC[C@@H]22)c2cc1
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Chemical Name(6aS11aS)-9-methoxy-6a11a-dihydro-6H-benzofuro[32-c]chromen-3-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Effect of lead treatment on medicarpin accumulation and on the gene expression of key enzymes involved in medicarpin biosynthesis in Medicago sativa L.Environ Sci Pollut Res Int. 2014 Dec;21(24):14091-8.
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