Glabrol
CAS No. 59870-65-4
Glabrol( —— )
Catalog No. M21683 CAS No. 59870-65-4
Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 224 | Get Quote |
|
| 10MG | 380 | Get Quote |
|
| 25MG | 617 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGlabrol
-
NoteResearch use only, not for human use.
-
Brief DescriptionGlabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
-
DescriptionGlabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
-
In VitroGlabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells.
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetP450
-
RecptorP450|NO Synthase|NF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number59870-65-4
-
Formula Weight392.49
-
Molecular FormulaC25H28O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (254.78 mM)
-
SMILESCC(C)=CCc(cc([C@H](C1)Oc(c(CC=C(C)C)c(cc2)O)c2C1=O)cc1)c1O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713.
molnova catalog
related products
-
Toddalolactone
anti-inflammatory and analgesic.
-
Alpha-Amyrin
Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.
-
LY 43578
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes.
Cart
sales@molnova.com