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Glabrol

CAS No. 59870-65-4

Glabrol( —— )

Catalog No. M21683 CAS No. 59870-65-4

Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 212 In Stock
5MG 187 In Stock
10MG 330 In Stock
25MG 548 In Stock
100MG Get Quote In Stock
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Biological Information

  • Product Name
    Glabrol
  • Note
    Research use only, not for human use.
  • Brief Description
    Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
  • Description
    Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
  • In Vitro
    Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    P450|NO Synthase|NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    59870-65-4
  • Formula Weight
    392.49
  • Molecular Formula
    C25H28O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (254.78 mM)
  • SMILES
    CC(C)=CCc(cc([C@H](C1)Oc(c(CC=C(C)C)c(cc2)O)c2C1=O)cc1)c1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713.
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