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3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid
3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid
CAS No. 168293-14-9
3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid( —— )
Catalog No. M21681 CAS No. 168293-14-9
3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid shows anti-inflammatory activity it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid
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NoteResearch use only, not for human use.
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Brief Description3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid shows anti-inflammatory activity it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells.
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Description3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid shows anti-inflammatory activity it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetNOS
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RecptorNO Synthase|NOS|PGE
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Research Area——
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Indication——
Chemical Information
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CAS Number168293-14-9
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Formula Weight512.72
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Molecular FormulaC32H48O5
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@@]12CC=C3C(=CC[C@]4(C)[C@@H]([C@@H](CC\C=C(/C)C)C(O)=O)[C@H](O)C[C@@]34C)[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Regaloside B
Regaloside B can inhibit the expression of iNOS and COX-2. Regaloside B is a phenylpropanoid isolated from Lilium longiflorum.It?has anti-inflammatory activity.
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AR-C102222
AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively; reduces inflammation produced by the application of arachidonic acid to the ear, attenuates FCA-induced mechanical hyperalgesia, and attenuates acetic acid-induced writhing in mice.Rheumatoid ArthritisDiscontinued
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MEG hemisulfate
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS in tissue homogenates.
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