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Dehydroeburicoic acid
CAS No. 6879-05-6
Dehydroeburicoic acid( —— )
Catalog No. M21680 CAS No. 6879-05-6
Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDehydroeburicoic acid
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NoteResearch use only, not for human use.
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Brief DescriptionDehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.
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DescriptionDehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.
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In VitroDehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI50 value of 40 μM.
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetNOS
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RecptorNO Synthase|TNF-α|NOS
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Research Area——
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Indication——
Chemical Information
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CAS Number6879-05-6
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Formula Weight468.73
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Molecular FormulaC3lH48O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 1 mg/mL (2.13 mM)
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SMILESCC(C)C(=C)CC[C@H]([C@H]1CC[C@@]2([C@@]1(CC=C3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C)C(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas.Chem Res Toxicol. 2009 Nov;22(11):1817-26.
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