Phentolamine

CAS No. 50-60-2

Phentolamine( —— )

Catalog No. M21648 CAS No. 50-60-2

Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
5MG 39 In Stock
50MG 110 In Stock
100MG 166 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Phentolamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist.
  • Description
    Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist.
  • In Vitro
    ——
  • In Vivo
    Phentolamine (5-20 mg/kg; i.p.) effectively inhibits the seizures elicited by strychnine (2 mg/kg, i.p.) and attenuates the seizure-potentiating effect of DOPS (4 mg/kg, i.p.) in mouse.Phentolamine (1 mg/kg; i.p.) increases insulin secretion by inhibition of b-cell a2A-adrenoceptors in mouse. Animal Model:WT miceDosage:1 mg/kg Administration:IP Result:Reduced blood glucose and increased insulin levels.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    α1-adrenergic receptor|α2-adrenergic receptor
  • Research Area
    Others
  • Indication
    Decrease in Night VisionDisturbance

Chemical Information

  • CAS Number
    50-60-2
  • Formula Weight
    281.36
  • Molecular Formula
    C17H19N3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1
  • Chemical Name
    Phenol 3-(((45-dihydro-1H-imidazol-2-yl)methyl)(4-methylphenyl)amino)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Goldstein I. Oral phentolamine: an alpha-1 alpha-2 adrenergic antagonist for the treatment of erectile dysfunction[J]. international journal of impotence research 2000 12:0-0.
molnova catalog
related products
  • Naphazoline

    Naphazoline is a sympathomimetic compound with marked alpha adrenergic activity.

  • Oxymetazoline hydroc...

    Oxymetazoline Hydrochloride is a selective alpha-1 agonist and partial alpha-2 agonist topical decongestant.Oxymetazoline is a selective alpha-1 agonist and partial alpha-2 agonist topical decongestant used in the form of Oxymetazoline hydrochloride.

  • BRL 44408 maleate

    A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.